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Because palmoplantar hyperkeratosis and alopecia can be detected in a fetus, parents may choose whether to continue the pregnancy. Genetic counselors can help parents with a difficult decision. You should read product labels, and discuss all therapies with a qualified health care provider. Natural Standard information does not constitute medical advice, diagnosis, or treatment. Palmoplantar hyperkeratosis and alopecia may be suspected based on observation of the distinctive qualities of the hair, skin, and nails. In addition, a detailed family history and complete physical examination must be completed. Unlike most forms of ectodermal dysplasia, palmoplantar hyperkeratosis and alopecia is associated with normal teeth and a normal ability to sweat. Hearing loss has been documented in some individuals with palmoplantar hyperkeratosis and alopecia. In a biopsy, a small sample of tissue is taken for analysis in the laboratory.
Mild side effects of retinoids include drought and chapped skin, hair loss is temporary, and the dryness of the eyes, mouth, and nose. Severe side effects of retinoids may include liver damage, increased blood cholesterol levels, excessive bone growth, in the palmoplantar hyperkeratosis and alopecia, the doctor can take a skin biopsy to assess the overall texture and the hair follicles and sweat glands. Individuals who have alopecia and palmoplantar hyperkeratosis may meet with a genetic counselor to discuss the risk of having a child with this disease. A genetic counselor can explain the options and the risks associated from various tests, including pre-implantation genetic diagnosis, amniocentesis, and chorionic villus sampling.
Birth defects if taken by pregnant women, headache, and swelling of the brain. People taking retinoids should be regularly monitored for side effects. In addition, women of fertile age have to undergo a pregnancy test on a regular basis. Pre-implantation genetic diagnosis can be used with in vitro fertilization. The embryos are tested for connexin genes are damaged, and only embryos unaffected can be selected for implantation. Retinoids, compounds that are related to vitamin A, which is known to soften the skin, and when taken by mouth, they can improve the skin and nail symptoms seen in palmoplantar hyperkeratosis and alopecia.